Patient: Please ask the following questions: 1. How harmful is having an ultrasound in early pregnancy to the baby and in what ways is it harmful? 2.What is the effect of doing hair in the first few days of pregnancy on the baby? (Dyeing and perming) 3. How much does the early pregnancy reaction affect the mother and the baby, and can I continue to work? I look forward to your answer, thank you! Qiao Xiaolin, Department of Obstetrics and Gynecology, Chaoyang Women’s and Children’s Hospital: 1. There is no evidence to prove that having a B-chair in early pregnancy has an effect on the baby. 2.Dyeing and perming hair in the first few days of pregnancy may cause birth defects in the baby and prenatal diagnosis is needed. 3.Severe early pregnancy reaction leading to ketoacidosis will affect the mother and the fetus and needs to be treated. Patient: Thank you, Mr. Qiao. Regarding the second question above, it is as follows: 1. last period was August 24 2. permed and dyed hair was on September 10 3. conception was between September 14 – September 21 (this can be confirmed) 4. period cycle is 31 days – 35 days Other conditions: I am 30 weeks old, this is my first child, and I have not had an abortion before. Regarding the above, what department should I go to in the hospital and when should I go for prenatal diagnosis? Qiao Xiaolin, Department of Obstetrics and Gynecology, Chaoyang Women’s and Children’s Hospital: The Obstetrics and Gynecology Department of the hospital regularly does prenatal checkups, Down’s syndrome screening at 14-18 weeks, amniocentesis at 18-24 weeks, and ultrasound screening for malformations at 20-24 weeks.