Numbness in the hands at night may be due to peripheral nerve damage caused by nerve damage in the hands due to long-term pressure on one side of the hand when sleeping on the side. Some patients also suffer from cervical spine problems, long-term sedentary work or long-term lying down to watch TV, resulting in a herniated cervical disc that compresses the nerve and causes numbness in the hand. In addition, diabetic patients who develop peripheral neuropathy may also experience numbness in the hands. There are also some rare causes of hand numbness, such as inflammatory radiculopathy in multiple hands, which can also cause Guillain-Barré syndrome. Regardless of the cause, if the symptoms persist and cannot be relieved on their own, and are accompanied by muscle weakness in the hands, which affects life and work, it is best to go to a specialized neurology department to identify the cause of hand numbness, so that better targeted treatment can be provided.