HPV type 18 infection, if persistent, can become cancerous after about 8 years. Because it takes 2-3 years from the infection of HPV type 18 to the development of low grade lesions in the cervical epithelium, and another 2-3 years from the low grade lesions in the cervix to the high grade lesions, and about 3 years from the high grade lesions to cervical cancer, the vast majority of patients will follow this pattern and develop lesions. However, for individual patients, the time to develop cancer may be shortened due to the poor resistance of the organism. Therefore, for HPV type 18 infection, high clinical attention should be paid to it, and regular checkups must be conducted, and if low grade lesions are found in the cervical epithelium, timely intervention should be made, mainly to eliminate the occurrence of cervical cancer.