Aerobic vaginitis is mainly caused by a decrease in the amount of lactobacillus bacteria in the vagina and an increase in aerobic bacteria. Commonly used medications are antibiotics, such as cefixime, etc., and some estrogens can be added if older women are ill. Since the vagina is not completely sterile, under normal circumstances there will also be parasitic flora, but these bacteria will not cause the body to fall ill. If the number of lactobacilli in the vagina decreases and the level of aerobic bacteria increases, it will lead to the occurrence of vaginitis, and cephalosporin antibiotics can be used to inhibit the reproduction of aerobic bacteria. If elderly women suffer from aerobic vaginitis, due to the decrease in estrogen content in elderly women, it will also lead to a decrease in the number of Lactobacillus flora, which will easily make the aerobic flora become the dominant flora. Therefore, cefixime can be used in addition to cephalexin, and some estrogens can be added to the aerobic vaginitis of elderly women. However, cefixime may lead to nausea, vomiting and other adverse reactions, and estrogen may lead to abnormal uterine bleeding and other adverse reactions, therefore, all of the above drugs should be used under the guidance of a professional doctor. If aerobic vaginitis is diagnosed, early and standardized treatment is recommended to reduce the adverse effects of the disease.