Clinical studies have observed that type 2 diabetes mellitus usually develops complications in about 10 years, mainly related to the control of blood glucose, the duration of the disease, and in case of acute complications, they can appear soon. Complications of diabetes mellitus are secondary diseases based on diabetes mellitus, which can involve organs of various systems of the body, such as heart, brain, kidney, nerves, retina, etc., and are more common in the elderly, patients with a longer history of the disease, and patients with poor glycemic control of diabetes mellitus. 1. Blood glucose control: the worse the blood glucose control, the earlier the complications appear; stable blood glucose control, the later the complications appear. There is a close relationship between stable blood glucose control and the occurrence of complications. 2. Duration of the disease: According to clinical statistics, diabetic peripheral neuropathy, diabetic retinopathy and other complications will appear after 5 to 8 years, and the complication rate is as high as 98% in 10 years. In addition, the complication time is also related to individual differences and the type of diabetes, the general individual physical condition is poor, type I diabetes complications occur earlier. It is recommended that diabetic patients be screened regularly for complications under the guidance of a medical professional.