During pregnancy, it is difficult for expectant mothers to avoid completely the injury of illness, possible bacterial and viral attack or unexpected trauma. When illness strikes, it is often confusing, worrying and confusing for many pregnant women to know whether they should apply medication or not, or if they have already used certain medication and are pregnant unexpectedly. In fact, it is difficult to answer precisely whether or not medication can be used during pregnancy, and which medications can be used, depending on the specific situation. Generally speaking, the first trimester of pregnancy should be used with special care, and the drugs that can be used or not should be used as much as possible, because this trimester is a critical period for the development and formation of various organs of the fetus, and is also the most sensitive period to various physical, chemical, biological, pharmaceutical and other external adverse factors stimulation, and taking certain drugs during this period may cause miscarriage or fetal malformation. If drugs are used 2 weeks after fertilization, i.e. before and after the onset of menstruation, the effect of drugs on the fetus will be in accordance with the law of “all” or “none”, i.e. either the effect will be serious and eventually miscarriage will occur, or there will be no effect or slight effect and the embryo will continue to develop without any abnormality. From 3 to 10 weeks after fertilization, the embryo is most susceptible to deformities caused by drugs, and this period is called “highly sensitive period for teratogenesis”. After the third month of pregnancy, the possibility of fetal malformation caused by drugs gradually decreases, but some drugs still have serious adverse effects on the fetus in the middle and late stages of pregnancy, such as tetracycline may affect fetal bone development, anti-inflammatory pain may cause premature closure of fetal artery ducts, sulfonamide may cause neonatal jaundice, etc. In addition, the size and duration of the drug have different effects on the fetus. The effects of drugs can be manifested as fetal structural abnormalities, growth restriction, functional defects and preterm delivery. The effects of different drugs on the fetus vary, and China has not yet classified the risk of drugs on the fetus during pregnancy. The U.S. Food and Drug Administration classifies drugs into five classes of A, B, C, D, and X according to their different degrees of teratogenic risks to animals and humans, and their risks increase in order. However, some drugs have two different risk ratings, one for the commonly used dose and the other for the extraordinary dose, which means that the same drug, applied at different times and doses, causes very different effects. Drugs with grade D and X should be avoided as much as possible during pregnancy. The first is that some people think that if you insist on not using drugs during pregnancy and use your own resistance to overcome the disease, you may be able to heal yourself if it is a minor ailment, but if it is a more serious disease, you may If the disease is very minor, it may heal itself, but if it is more serious, it may delay treatment and cause the disease to escalate and worsen or become chronic, requiring more effort to treat, which will have a greater impact on the fetus. Secondly, some people think that it’s okay for adults to suffer from illnesses, and for the sake of the baby, all the suffering can be endured, but this is actually a very wrong idea, the environment in the womb is closely related to the overall state of the mother, if the mother is very sick, she can’t protect herself, how can she ensure the healthy growth of the fetus? Therefore, you should not take it upon yourself not to treat your illness during pregnancy, but should go to a regular hospital for consultation and try to use medication rationally. For chronic diseases, such as hypertension, diabetes, heart disease, hyperthyroidism, connective tissue disease, etc., you should go to the hospital for consultation before preparing for pregnancy and adjust the treatment plan as early as possible. For those who suffer from acute diseases or diseases that can be cured within a certain period of time, such as tuberculosis, acute or active hepatitis, tumors, trauma, etc. should be cured urgently before pregnancy. The most common illness during pregnancy is a cold. Do I need to take medicine after a cold? If you have a mild cold, you can drink more water, take more rest and take some vitamin C. But if you have a serious cold, especially if you have fever, you should give medication, you can choose some anti-viral herbal medicine such as Banlangen, and take vitamin C or eat more fruits and vegetables rich in vitamin C. Cold medicine containing antipyretic and analgesic ingredients such as acetaminophen can relieve headache, fever, runny nose and other symptoms. It is safe to apply for a short time during pregnancy. Here are some common drugs that are classified as safe in pregnancy for the reference of mothers-to-be: 1. The drugs classified as belonging to category B, which are safer to apply in early pregnancy are: most vitamins (in appropriate doses), penicillins, cephalosporins, erythromycin, azithromycin, clindamycin, clotrimazole, mycobacterium, ethambutol, luminal, ibuprofen, fotarine, acetaminophen (Benadryl, Pepcid, Tylenol). Piriton, Tylenol), Benadryl, Paracetamol, Promethazine, Keratan, Ursodeoxycholic acid, Insulin, Low molecular heparin, Dacrypromine, Remitidine, Famotidine, Simethicone, Thioglycollate, Gastric Enzyme Combination, Dried Yeast Tablets, Magnesium Sulfate. 2, drugs belonging to class C, animal experiments harmful to the fetus, and humans have not been able to do adequate research, can not be sure of their safety of drugs are: spiramycin, clarithromycin, butamycin, gentamicin, haloperidol, ciprofloxacin, ofloxacin, sulfadiazine, isoniazid, rifampin, dacrynic acid, fluconazole, ketoconazole, acyclovir, hydrazidiazide, labetalol, cardiac pain, lorvastatin, Tramadol, methyldopa, phentolamine, flupromazine, xylazine, aspirin, anti-inflammatory pain, hypoglycemic, carbamazepine, lorcet, morpholine, cisapride, salbutamol, aminophylline, pansentin, tachyphylaxis, oral contraceptives, prednisone, dexamethasone, betamethasone, etc. Such drugs may be potentially dangerous to the fetus, but when a pregnant woman’s condition is serious and may affect the health of the fetus, i.e., treatment with drugs The benefits to the pregnant woman are greater than the harm to the fetus. 3, Class D drugs: streptomycin, tetracyclines, sodium nitroprusside, Kepone, morphine, dulcolax, valium, phenytoin sodium, anti-epileptic drugs, propylthiouracil, iodide, lithium salt, some anti-cancer drugs, dihydrocoumarin, warfarin, etc., such drugs have been clearly harmful to the fetus, in general, pregnant women are prohibited, but when pregnant women have serious illness or life-threatening need to rescue can still be considered for application. 4, X drugs: in animal or human studies have shown that it can be seriously harmful to the fetus, pregnant women are prohibited, such drugs are: ribavirin (virus azole), radioactive iodine, hexestrol, danazol, mifepristone, most anti-cancer drugs such as cyclophosphamide, methotrexate, fluorouracil, etc.. In short, the principles of medication during pregnancy are: 1. mothers-to-be of childbearing age who are preparing to become pregnant should be careful with medication; 2. those with acute and chronic diseases should be treated before pregnancy; 3. non-essential drugs should be used sparingly during pregnancy, especially during the 3 months; 4. termination of pregnancy should be considered after using obvious teratogenic drugs during early pregnancy; 5. diseases during pregnancy should be treated promptly; 6. drugs with more definite conclusions should be used, and new drugs should be used as little as possible; 7. 7. Chinese medicines can generally be implemented according to the instructions of “caution” or “prohibition” for pregnant women.