Whether or not intestinal mucosa detachment can heal on its own usually depends on the situation. Very few adult patients with strong immune function or newborns in growth and development may heal themselves after the appearance of intestinal mucosa shedding; however, in most cases, patients need to cooperate with active treatment such as medicine and surgery to achieve cure: 1. May heal itself: Patients with mild inflammatory bowel disease who have intestinal mucosa shedding may appear to heal themselves with positive body immune function. In addition, a small number of newborns in diarrhea, indigestion, defecation, may appear part of the gastrointestinal mucosa tissue shed discharge, but through the intestinal cells constantly updated, shed, regeneration, to a certain extent may achieve self-healing; 2, not self-healing: general intestinal inflammatory diseases, such as rectal prolapse, intestinal mucositis, ulcerative colitis and other patients caused by intestinal mucosa shed, accompanied by infection, abdominal pain, diarrhea and other symptoms. Therefore, timely and standardized drug treatment is needed to achieve the purpose of cure. As for the symptoms of intestinal mucosal detachment caused by intestinal occupational lesions, such as rectal neurofibroma, colon polyps, colorectal cancer, etc., which may be life-threatening in serious cases, patients need to receive timely treatment in hospitals to avoid delaying the condition and causing adverse consequences.