Wake up in the morning panic wrist swelling, the reason may be the existence of cardiac arrhythmia or the occurrence of kidney disease, according to the cause of choice of conservative or drug treatment. 1. Arrhythmia: Arrhythmia in the morning can appear panic, chest tightness and other manifestations, if there is cardiac insufficiency, can cause cardiogenic edema manifestations, but often occurs in the lower limbs, wrist swelling is rare, but not excluded. It is recommended to improve the electrocardiogram, cardiac ultrasound examination, occasional arrhythmia can not use drugs; if there are serious arrhythmia and cardiac insufficiency, can take amiodarone or digitalis and other treatment. 2. Kidney disease: when there is glomerulonephritis or nephrotic syndrome, resulting in renal hypoplasia, a large amount of water and sodium retention can occur in the body, and typical swelling of the hands and panic attacks can be seen when waking up in the morning. Urine routine, kidney puncture and other tests should be checked. If there is nephritis or nephropathy, most symptomatic treatment can be enough, you can use captopril and so on to control high blood pressure, serious kidney disease should be treated with glucocorticoids, such as prednisone. Therefore, if you wake up in the morning with panic attacks and swelling of the wrists, you should consult a doctor in time, complete the relevant examinations, make a clear diagnosis and then treat the cause under the guidance of the doctor.