Geriatric vaginitis with vulvar itching can be treated with topical or systemic anti-infective medications, and if necessary, estrogen preparations can be taken to regulate organ function. Topical medication, potassium permanganate baths or topical antibiotic ointment can be used to fight infection. Penicillin and clindamycin can also be applied according to the results of drug sensitization. In addition, estrogen can be supplemented, such as combining with estrogen ointment, to improve the function of the organism, thus reducing the possibility of the organism being attacked by pathogens. Due to the gradual decline of body functions, immunity and resistance of middle-aged and elderly women are relatively low, easy to be attacked by bacteria and other pathogens, thus causing vaginal inflammation or other lesions. Therefore, it is more important to pay attention to personal hygiene in daily life to avoid infection. Patients with senile vaginitis should go to a regular hospital for treatment if the vulvar itching is severe. The use of the above drugs should be strictly in accordance with medical advice.