1.Serum enzymatic tests: important ones are glutamic aminotransferase, glutamic oxalacetic aminotransferase, alkaline phosphatase, γ-glutamate transpeptidase. 2, serum bilirubin metabolism: test serum bilirubin does not reflect the presence of hepatic sclerosis, but can indicate the nature of jaundice. In hepatocellular jaundice, both direct and indirect bilirubin in the blood are increased, with indirect bilirubin being the predominant increase. 3.Serum protein measurement: there are total serum protein, albumin, globulin, and albumin/globulin ratio. Protein metabolism is an important manifestation of the liver’s metabolic capacity, and is a reflection of the damage caused by chronic liver disease. In cirrhosis, albumin synthesis is often reduced, and the albumin/globulin ratio in blood is reduced or even inverted. The lower the ratio, the worse the liver’s ability to compensate. 4, protein electrophoresis: protein electrophoresis appears, γ-globulin ratio increases, revealing chronic liver disease. The increase in γ-globulin is most significant in post-hepatitis cirrhosis loss of compensation. 5, prothrombin time measurement: when the liver parenchymal cells are damaged, the liver synthesis of a variety of coagulation factors can be reduced. When liver function is severely impaired, prothrombin time measurement a more sensitive indicator, prothrombin time prolonged in the advanced stage of cirrhosis. 6.Immunoglobulin measurement: post-hepatitis cirrhosis is more common with increased IgG and IgA, mostly with increased IgG. IgM is increased in primary biliary cirrhosis, and IgA is increased in alcoholic cirrhosis. 7.Serum total cholesterol and cholesteryl ester measurement: both are decreased in cirrhosis. 8, liver fibrosis indicators: proline hydroxylase, hyaluronic acid, subtype precollagen peptide, monoamine oxidase, etc., all have different degrees of increase in cirrhosis.