1. High-resting position at night. Limit salt and give diuretics. 2, 1% methylcellulose or 0.5% hydrocortisone eye drops. Use antibiotic ointment during sleep, cover the eyes to prevent corneal damage. 3.Immunosuppressant;Prednisone 60-100 mg orally in 3 divided doses for 2-4 weeks, and then gradually reduce the dose in the following 4-12 weeks. Severe cases can be applied to methylprednisolone 0.5-1.0 grams added to saline drip, every other day, every other day, 2-3 times in a row after changing to oral prednisone. Other immunosuppressants such as cyclophosphamide can also be used. 4, severe protruding eyes, exposure keratitis or pressure through the visual extension through the lesion, feasible orbital decompression surgery or retrobulbar radiation therapy, in order to reduce the orbital and retrobulbar infiltration. When prednisone is not effective. It can be changed to retrobulbar radiation therapy, usually given 20GY dose, divided into 10 times in 2 weeks. 5.ATD treatment is preferred for controlling hyperthyroidism, as surgery and iodine-131 treatment may aggravate invasive proptosis. 6, Euthyrox 50-100MG can be combined to prevent hypothyroidism from aggravating proptosis.