Colorectal cancer (commonly known as colorectal cancer) is one of the most common cancers in the world, accounting for about 10% of the global cancer incidence rate. In China, colorectal cancer ranks third in the incidence ranking of malignant tumors. Colorectal cancer is preventable and treatable, and can be detected and treated early through preventive screening. Compared with other malignant tumors, colorectal cancer has made significant progress in diagnosis and treatment; the five-year survival rate for stage I colorectal cancer patients is 90%, and 80% for stage II colorectal cancer patients; while the survival rate for stage III colorectal cancer patients is only 35%. The incidence of colorectal cancer is closely related to lifestyle Colorectal cancer is a malignant tumor originating from the epithelial tissue of the large intestine, including colon cancer, rectal cancer and anal canal cancer, which is one of the most common malignant tumors. The incidence rate, incidence site and incidence age of colorectal cancer are increasing. According to the data, the average annual incidence of colorectal cancer in China is 130,000, and the average annual increase is 4%, among which the incidence of colon cancer is more significant and the proportion of colorectal cancer is gradually increasing. According to the latest statistics, the proportion of young people under 40 years old suffering from colorectal cancer accounts for about 20% of the total number of colorectal cancer cases. China has entered the ranks of regions with high incidence of colorectal cancer. Although the causes of colorectal cancer are complex, the incidence of colorectal cancer is closely related to lifestyle, such as high protein, high fat, low fiber diet, frequent consumption of fried and pickled foods, and lack of physical exercise can increase the incidence of colorectal cancer. In addition, patients with certain intestinal diseases, such as chronic inflammation of the intestine, polyps and adenomas, schistosomal colitis and ulcerative colitis, are prone to develop colorectal cancer. At the same time, for those who have family members who have had colorectal cancer, the risk of colorectal cancer in the immediate family is higher, so for those who are at high risk of colorectal cancer, they should actively undergo regular checkups. Colorectal cancer is easy to detect early compared to other tumors Colorectal cancer is a disease that can be fatal, but fortunately, it can be effectively prevented through reasonable measures. The most important thing is to change the high-fat, high-protein, low-fiber diet and early detection (endoscopy) of pre-cancerous lesions such as colorectal adenomas, and interrupt the cancer process through active intervention (endoscopic removal). For people with high risk of colorectal cancer, colonoscopy should be performed regularly. In addition, precancerous lesions of colorectal cancer should be actively treated, and more than 80% of colorectal cancer is transformed from colorectal adenoma. People with the following symptoms should pay attention to the existence of colorectal cancer, mainly referring to blood in stool, change of stool shape and change of stool habit. Blood in stool is the most common clinical manifestation of colorectal cancer. Most patients with colorectal cancer combined with bleeding do not have blood in stool alone, but have pus and mucus in stool. Change of stool shape: When the volume of rectal and anal canal tumor increases to a certain extent, the shape of stool often changes, which is manifested as thin stool and deformation. Change of stool habit: mainly change of bowel frequency, including diarrhea, constipation, alternating diarrhea and constipation, feeling of incomplete bowel movement, difficulty in bowel movement, etc. Early detection of colorectal cancer mainly relies on reasonable screening, rather than waiting for symptoms to appear before examination. The population can be divided into three categories, and different groups receive different screening programs. General population: people who are not at high risk of colorectal cancer, we recommend that these people can start to receive screening for colorectal cancer after the age of 45, and on average, they should be examined once every 5-10 years, and the examination methods mainly include fecal occult blood and colonoscopy. For high-risk groups, excluding those with family history, we recommend to start screening for colorectal cancer around the age of 40, with an average of once every 3-5 years. People with family history: For people with family history, we recommend going to a large hospital as early as possible to determine whether the group has a genetic predisposition through careful collection of family history and some necessary tests, including genetic testing, by experienced clinicians. If there is a genetic predisposition, then the clinician will follow up closely according to the specific follow-up protocol for hereditary tumors. If there is no apparent genetic predisposition, the population is followed up according to the screening protocol for high-risk groups. Early detection of colorectal cancer is a curable disease A better staging system can be established using molecular genetic surveillance; surgical techniques can be improved to reduce post-operative mortality and recurrence rates; and the advent of highly effective therapeutic drugs has led to the continuous updating of colorectal cancer treatment protocols, resulting in longer survival and better quality of life, and even early stage patients can be cured. Over the past decade, new chemotherapeutic agents and molecularly targeted therapies have led to significant improvements in the treatment of metastatic colorectal cancer. This has led to significant increases in tumor remission rates and improvements in patient survival and quality of life.” In the treatment of advanced colorectal cancer, lexadine in combination with 5-FU/LV resulted in a 9.2% overall chance of survival at 5 years for patients with advanced disease, a regimen whose 5-year overall survival results set a new benchmark in the first-line treatment of metastatic colorectal cancer. Among human malignancies, especially those of the gastrointestinal tract, colorectal cancer is one of the best treated tumors. A significant proportion of patients with colorectal cancer can be completely cured through a multidisciplinary and comprehensive treatment based on surgery.