Pediatric oral herpes is a disease caused by the herpes simplex virus and occurs in children between the ages of six months and two years. Some young children may present with fever, headache, and swollen lymph nodes. Oral herpes is usually treated with systemic antiviral therapy, local treatment, symptomatic and supportive therapy. 1, systemic antiviral treatment: you can usually take acyclovir, which is the most widely used anti-herpes virus drug for herpes. At the same time, some drugs that have a clearing and detoxifying effect can also help the condition recover quickly. The specific should be taken according to the doctor’s guidance. 2, local treatment: It is recommended that children with oral herpes use local medication for oral mucosa, common solutions include compound boric acid solution; chlorhexidine oral solution preparation with gargle; these local medications help to clean and disinfect the oral cavity, which can reduce the chance of bacterial infection. If oral herpes recurs, it is recommended to use helium-neon laser for local irradiation. 3, symptomatic and supportive therapy: If oral herpes in children is very serious, bed rest is recommended, do not do strenuous activities, if there are symptoms such as difficulty in eating, it is extremely easy to lead to dehydration, nutritional disorders and other problems, bringing danger to the life of the child, need to give timely intravenous hydration as well as nutrients. Oral herpes is self-limiting and can easily recur. Usually children with oral herpes are recommended to take several of the above methods for treatment. If the condition is serious go to the hospital in time.