Bronchitis eat azithromycin did not work is mainly considered to be the drug course is not enough, the patient’s resistance to drugs, the pathogenic bacteria are not sensitive to the drug, or there is no medication error caused by the cause of the medication, usually can be appropriate to extend the time of use of the drug, or replacement of the use of other types of antibiotics or antiviral drugs to treat. Azithromycin belongs to the class of macrolide antibiotics, effective for mycoplasma infections or infections caused by some sensitive bacteria, bronchitis is mainly caused by viral or bacterial and other infections. If the bacterial infection caused by bronchitis, take azithromycin did not work, it may be that the drug is not enough to use the course of treatment, the need to extend the treatment time appropriately; or the patient is resistant to the drug, the pathogenic bacteria are not sensitive to this class of antibiotics, can be replaced with quinolones, penicillins, cephalosporins and other antibiotics to treat, such as levofloxacin, amoxicillin, cefixime and so on. If the bronchitis is caused by a viral infection, the use of azithromycin to treat it is not the right medicine, and will not achieve the therapeutic effect. Virus-induced bronchitis is self-limiting and usually does not need to be treated with antiviral drugs, but if the patient’s immune system is defective, the use of antiviral drugs such as amantadine and ribavirin can be replaced. It is recommended that patients go to the hospital for timely examination and be instructed to change the medication after the doctor clarifies the causative agent causing bronchitis. If there is any discomfort after using the medication, the patient should consult a doctor promptly. The above medications should be used under the supervision of a physician.