Clofazimine: phenazine derivative, also known as chlorophenothiazine. Clinical applications: 1. It has certain efficacy on leprosy of tumor type and leprosy reaction. Treatment of cases resistant to aminophenazone or causing leprosy reactions. 2. For Mycobacterium tuberculosis and sensitive multi-drug resistant Mycobacterium tuberculosis infection. Xie Xiaoyan, Department of Pharmacy, Hebei Chest Hospital 3.Used in combination with rifampin or ethionamide for the treatment of infections caused by strains of sulfone-resistant bacteria. 4.Used for erythema nodosum leprosy reaction and acute leprosy reaction caused by other drugs. 5.Used in combination with other anti-tuberculosis drugs for AIDS patients with concomitant atypical mycobacterial infections.