Blood in the stool in cirrhosis is due to the development of portal hypertension in cirrhosis, which leads to the establishment of collateral circulation, esophagogastric-fundus venous varices or the development of portal hypertensive gastropathy. When eating harder food can cause the varices to rupture and bleed, or the development of ulcers in portal hypertensive gastropathy leads to bleeding, which can manifest as vomiting blood or blood in stool. Vomiting blood usually indicates a large amount of bleeding, while blood in the stool usually manifests as black stool with a tar-like color. Blood in the stool is the most common complication of advanced cirrhosis, and hemorrhagic shock can occur with heavy bleeding, which can also induce hepatic encephalopathy. If the blood in the stool, the patient must rest in bed, abstain from food and water, and apply hemostatic drugs to stop the bleeding. If hemostatic drugs are not effective, endoscopic hemostasis can be considered by applying injectable sclerosing agents or tissue adhesives to the varicose veins, which can not only achieve the purpose of hemostasis, but also effectively prevent rebleeding.