The location of the onset of vitiligo is different for each person and there is no fixed statement. Vitiligo can occur in any part of the skin and is more likely to occur in areas susceptible to light and friction, such as the face, neck, trunk and extremities, and the mouth and lips, external genital mucosa, and the inner mucosa of the foreskin can also be involved. The lesions are often symmetrically distributed, but can also be segmentally distributed along the nerve line, and appear as limited spots of complete pigment loss, milky white, varying in size and shape, and can be round, oval or irregular white spots, and the hair at the white spots can also turn white. In the progressive stage, the depigmented spots move towards the normal skin and develop faster, and may have an isomorphic reaction. In the stable stage, the white spots stop developing, with clear boundaries and pigmented rings around the edges. Different treatments have to be chosen according to the stage and the individual differences of each person.