Ulcerative colitis is a chronic disease that often recurs and requires long-term treatment, and aminosalicylates and immunosuppressive drugs are generally used clinically. It is also very important to regulate the balance of the gastrointestinal tract flora. Probiotic preparations commonly used in clinical practice include Bifidobacterium bifidum triplex, Bacillus cereus, Clostridium typhimurium live, Clostridium typhimurium enterococci triplex and Lactobacillus tablets. These probiotics can adhere to the intestinal mucosa after reaching the intestine and can prevent the adsorption of pathogenic microorganisms in the intestine, which can inhibit the colonization or overgrowth of pathogenic bacteria, so they are often used in the treatment of ulcerative colitis.