Periungual warts do not usually heal on their own, but in a very small number of patients there may be a chance that they will heal on their own when their immune status is strong. Periungual warts are lesions produced by human papillomavirus infection in the periungual area, invading partially around the nail bed where the capillaries are more dense. The chances of developing warts are generally increased in immunocompromised conditions and may also be exacerbated. Human papillomavirus infection, there are some self-healing ability, if the person’s body resistance is relatively high, the disease is relatively mild, and there is no other disease, then the patient can be in daily life through the diet to maintain nutritional balance, to maintain a good state of nutrition, enhance their own immunity, in this case, periannual warts have a certain self-healing possibilities. If the patient’s immune system is low, and the warts are more serious, it is difficult to complete the self-healing. If you don’t take an active part in the treatment, the warts may get bigger, and even the nail bed may become infected. In this case, you need a combination of medication, physical therapy and surgery to achieve a cure. It is advisable to go to the hospital in time, under the guidance of the doctor to standardize the treatment.