Many patients wonder what male factors should be taken into account in IVF treatment, whether malformed sperm affects IVF outcomes, and whether malformed sperm can cause malformed fetuses. To find out the answers to these questions, please read on. After nearly 40 years of development, IVF technology has made great strides, but still has a lingering success rate. Experts from all over the country discussed hot and difficult issues in the field of male medicine and reproduction, and after heated debates and careful arguments, the expert committee concluded that it is important to consider male factors in the IVF technology process to improve the success rate of IVF. Finally, the expert committee reached a consensus on the male factors that may affect IVF outcomes as follows: 1. Age: It is well known that female age is an important killer of fertility. For men likewise, male fertility is best around the age of 30, and male sperm quality tends to decline as age increases. 2, obesity: male weight affects the outcome of in vitro fertilization. Studies have shown that male body mass index (BMI) R25kg/m2, the clinical pregnancy rate of assisted reproduction significantly decreased. 3, deformed sperm: deformed sperm may affect the fertilization rate (including natural conception and assisted reproduction), but deformed sperm has no effect on abnormal fertilization (such as multiple sperm fertilization), the number of embryos obtained, embryo quality, and the success rate of implantation, and has little correlation with embryonic arrest, abnormal fetuses, and preterm birth. 4. Sperm DNA integrity (sperm fragmentation rate, DFI): Sperm DNA damage is closely related to IVF outcome, which can cause fertilization failure, embryo abnormalities, and is closely related to miscarriage, preterm birth, and birth defects. Therefore, it is important to pay attention to sperm NDA integrity testing, which is crucial for determining IVF outcomes. 5. Sperm RNA testing: Sperm RNA is important for assessing sperm vitality, fertilization ability and developmental potential of embryos after fertilization. Therefore, RNA testing is of some significance to accurately assess male fertility and determine IVF outcomes. This test is still in the laboratory stage and should be actively carried out in the clinic.