Overview of Ahom’s disease

  Ahun’s disease is a relatively rare condition for which there are no specific scientific studies in the world and the pathogenesis is still unclear. Nonetheless, it is important to get a proper overview of this pathology. The following is an overview of Ahun’s disease.  Ahun’s disease, also known as anehum, dactylolysis, or dactylolysisspontanea, is an endemic disease of the tropics. Due to chronic inflammatory fibrosis, the toe (finger) is linearly narrowed and finally forms a finger (toe) detachment.  Pseudoainhum refers to the circumferential narrowing of the toe (finger) associated with certain genetic or non-genetic disorders. It is often associated with hereditary diseases such as palmoplantar keratosis, Meleda disease, linear keratosis, erythroderma, congenital thick nail syndrome and congenital ectodermal defects, etc. It can also be seen in leprosy, scleroderma, Raynaud’s syndrome, cremasteric myeloma, frostbite, trauma and burns.  Wells et al. divided the constricted bands occurring in the extremities into four categories: (1) Ahun’s disease; (2) congenital constricted bands; (3) Ahun’s-like bands complicated by other diseases; and (4) secondary bands caused by trauma.  Neumann refers to the latter three collectively as pseudo-Ahun’s disease, which is usually associated with some kind of genetic or non-genetic disease. Genetic diseases include disfiguring palmar toe keratoderma, striated palmoplantar keratoderma, hairy red furunculosis, etc. Non-genetic diseases include cremaster cavernosa, cervical spondylosis, scleroderma, Raynaud’s disease, syphilis, etc. Treatment may include zigzag surgery to excise the constricted band, and intra-dermal injection of betamethasone has also been reported.  The name Ahon is derived from the ancient word for “sawing” in the East. The disease was first mentioned by Messue in 1821 as a skin abnormality with bone resorption of unknown origin, and is an endemic disease occurring in tropical and subtropical regions. The main feature is the appearance of constricting bands around the fingers (toes).
band). It is spontaneously amputated.  The disease starts with a high incidence in blacks. At the beginning of the disease, the skin of the distal interphalangeal joint is cracked, the dermis forms a ring-shaped fiber, a transverse groove appears and gradually deepens, eventually forming a ring-shaped groove, like being strangled by a thin rope, the distal finger and toe of the ring-shaped groove is swollen and can be painful, vesicular and smelly. The annular groove becomes deeper and deeper. Generally, the fingers (toes) are naturally truncated in 5~10 years. Due to blood and nerve dystrophy. The local bone is progressively resorbed with the deepening of the soft tissue sulcus. The stump becomes sharp and pointed. The histological examination is osteoporotic bone.  Medicine is always endless, and we should explore the conditions that have not been studied yet, like Ahun’s disease. At the same time, for the sake of our own bodies, we should always exercise, life is in motion.