Fungal infection on the hands is tinea cruris, topical medication is the main treatment, oral medication can be considered when the effect is not good. Tinea versicolor is a superficial skin fungal infection of the hands caused by dermatophytes, which can appear as blisters, flaking, rough and thickened skin and other lesions, and can spread to other parts of the body if it is not actively treated, leading to onychomycosis, tinea cruris, and tinea corporis. The treatment of tinea cruris is based on topical medications, including clotrimazole, miconazole, naftifine and amorolfine. Simply using topical antifungal drug treatment, the effect is fast, low cost, but the course of treatment is longer. If the efficacy is unsatisfactory, a combination of oral and topical antifungal drugs can be considered. Oral drugs include terbinafine, itraconazole and so on. The use of drugs should be under the guidance of medical professionals to avoid adverse reactions. It is recommended that patients go to the hospital in time and follow the doctor’s instructions for standardized treatment.