There is no cure for Gaucher’s disease, so patients will not be completely cured after a splenectomy.
Splenectomy is not the treatment of choice and is only considered when there is recurrent splenic infarction resulting in unrelieved abdominal pain, severe restrictive lung disease, etc. Splenectomy can significantly improve clinical symptoms, reduce anaemia and bleeding tendencies and improve developmental status. However, large amounts of metabolic material accumulate in the liver and bones after splenectomy and may accelerate hepatomegaly and bone destruction, so splenectomy should be delayed as much as possible and partial splenectomy may be considered if necessary.