Nephrotic syndrome is a chronic kidney disease with long treatment period and complicated medication. Western medicine treats this disease, mostly with hormones or other immunosuppressive drugs, and its larger side effects are troublesome while treating the disease. During high doses of hormone therapy, children will be very excited, have difficulty sleeping at night, have a very good appetite, gain weight rapidly, and grow acne in older children. When hormones are reduced to small doses, they will show loss of appetite, sweat a lot, cough often, and catch colds easily. In fact, if these side effects are combined with herbal treatment, the degree will be much less and the child will not feel so uncomfortable. Specifically, Chinese herbal medicine is used in phases with hormone treatment method. In the phase of high dose of hormone, Chinese herbal medicine that nourishes Yin and reduces fire is used, in the phase of hormone reduction, Chinese herbal medicine that benefits Qi and nourishes Yin is used, and after the maintenance or discontinuation of small dose of hormone, Chinese herbal medicine that warms Yang is used appropriately. A large number of clinical experiences have confirmed that the combination of Western medicine and Chinese medicine can reduce the side effects of Western medicine at the initial stage and reduce recurrence and maintain stability at the later stage. Therefore, if possible, parents should try to choose the combination of Western and Chinese medicine treatment.