Drugs for cleaning the anus include potassium permanganate, saline, etc., which can be used in accordance with medical advice. 1. Potassium permanganate: potassium permanganate is commonly used in acute dermatitis, acute eczema ulcer surface cleaning, but also used for snakebite first aid, fruit or tableware disinfection. When using potassium permanganate to clean the anus, it should be prepared as 1:5000 potassium permanganate solution to reduce the irritation and damage caused to the local skin and mucous membrane. 2. Saline: a common clinical solution, which can be used externally to rinse the eyes, wash wounds, etc. It can also be used for intravenous infusion. Usually using saline to clean the anus can improve comfort, prevent anal inflammatory diseases and will not irritate the skin in the anal area. For people who are healthy and do not have any anal disease, daily rinsing of the anal area with lukewarm water is sufficient, and no special medication is needed. It is also important to wear loose-fitting, cotton underwear as much as possible to avoid foreign body friction and irritation. It is recommended that people with anal lesions follow the doctor’s instructions to use medication, do not self-medication or gullible prescription, in order to prevent aggravation of the condition.