I. What is Mycoplasma urealyticum Mycoplasma urealyticum (M. urealyticum) is the only one species in the genus Ureaplasma, named because of the need for urea for growth. Colonies are tiny, only 15~25um in diameter, and must be observed under a low power microscope, so the old name T strain (tiny strain). The surface of the colony has rough particles, which can be turned into a typical ruffled egg-like colony under suitable conditions. It needs cholesterol and urea for growth, and its metabolism is characterized by the decomposition of urea, which produces ammonia nitrogen and increases the pH of the culture medium, and patients often have a foul smell in their urine. Mycoplasma solani is widely distributed in nature. In addition to humans, many animals such as cats, cattle, chickens, dogs, ducks, sheep, horses, rats, monkeys, pigs and pigeons, as well as insects and plants, are capable of carrying and storing this pathogen. Epidemiological surveys have shown that Mycoplasma solani can be isolated from 34% of normal males and can host up to 50-80% of pregnant women in their lower genital tract. This is because there are many subtypes of UU, some pathogenic and some non-pathogenic. However, due to the limited availability of tests, it is not possible to distinguish between pathogenic and non-pathogenic UU. If the test for mycoplasma is positive, but there are no symptoms, you are a mycoplasma carrier. The Western medicine has a low cure for mycoplasma urealyticum, and it is believed that patients taking antibiotics for a long time are more harmful to their health, and it is proposed that carriers do not need to be treated. The transmission of Mycoplasma solani infection: Mycoplasma solani (UU) often resides in the human genitourinary tract and can lead to genitourinary infections when the body’s resistance decreases, mainly through sexual transmission, but do not be nervous, not a sexually transmitted disease. It is often seen in the young sexually active period, especially after unclean intercourse. When the genitourinary tract is inflamed and the mucosal surface is damaged, Mycoplasma urealyticum can easily invade through the breach and cause genitourinary tract infection. Most patients have no obvious symptoms after Mycoplasma urealyticum infection, so it is difficult to be detected by patients, and it is also easy to be missed by doctors. Mycoplasma urealyticum can invade the urethra, cervix and vestibular gland, causing urethritis, cervicitis and vestibular glanditis; when infected upstream, it can cause endometritis, pelvic inflammatory disease and tubitis, especially tubitis. Pathological changes in female reproductive organs caused by Mycoplasma hyopneumoniae infection are an important cause of infertility. Domestic and foreign data suggest that the culture positivity rate of Mycoplasma urealyticum in cervical mucus and semen of infertile couples is more than 50%, which shows that there is a correlation between Mycoplasma urealyticum infection and the occurrence of infertility. Another cause of poor performance due to Mycoplasma urealyticum infection is miscarriage, and some people have examined the tissue from miscarriages with a positive rate of Mycoplasma urealyticum up to 40% or more. Therefore, the possibility of having Mycoplasma urealyticum infection should be considered for unexplained miscarriages, especially in those with multiple miscarriages. The inflammatory adhesions of incompletely obstructed fallopian tubes caused by Mycoplasma solium infection can narrow the lumen and make it inaccessible, and are also an important cause of ectopic pregnancy. The incubation period is 1-3 weeks, and inflammation of the reproductive system centered on the cervix is seen in female patients. When the infection spreads to the urethra, frequent and urgent urination is the main symptom that draws the patient’s attention. When the infection is confined to the cervix, the symptoms are increased leucorrhea, cloudiness, edema, congestion or surface erosion of the cervix. If the infection spreads to the urethra, the urethral orifice is flushed and congested, and a small amount of discharge can be spilled by squeezing the urethra, but pressure pain is rarely present. (1) Mycoplasma urealyticum has the closest relationship with women’s reproductive health. Mycoplasma urealyticum can cause genitourinary tract infections and is considered to be the second most important pathogen after Chlamydia (50%) in non-gonococcal urethritis. Since 80% of pregnant women have Mycoplasma solium in their genital tract, it can infect the fetus through the placenta and cause premature birth, stillbirth, or infect the newborn during delivery and cause respiratory infections. In addition, Mycoplasma urealyticum can also cause infertility. (2) After pregnancy, women are more susceptible to infection by Mycoplasma urealyticum because of the increase in progesterone, which suppresses cellular immunity and decreases the body’s resistance. Mycoplasma urealyticum can be transmitted vertically through the placenta or spread upstream by infection in the lower genital tract of pregnant women, causing intrauterine infection, both of which can lead to abortion, preterm delivery, intrauterine growth retardation, low birth weight, premature rupture of fetal membranes, and even fetal death in the uterus. (3), during delivery, the fetus is also susceptible to infection when delivered through the birth canal. The common ones are neonatal ophthalmia, followed by neonatal respiratory tract infection, and other otitis media and laryngitis. The first thing you need to do is to take care of the problem. Treatment: 1. It is best to do a drug sensitivity test and treat with a high dose of drugs for 1 week or a conventional dose for 14 days according to the drug sensitivity. Clinical treatment is not very effective, found to be coupled with broad-spectrum antibiotics. 2, couples with treatment, tool contraception during treatment, stop medication 3 weeks review; 3, not pregnant women can take Mymogenicin, erythromycin and other drugs, pregnant women are limited to treatment with erythromycin.