Vitiligo is not life-threatening, vitiligo is skin pigment loss, resulting in the appearance of skin white spots, vitiligo in the vast majority of cases only affects the aesthetic, very few vitiligo patients ocular pigment epithelium or choroidal melanocytes destruction, will lead to uveitis, choroidal retinal decoloration and pigmentary retinitis, may affect vision, if the cochlear melanocytes are involved, can lead to hearing loss. The cause of vitiligo is unknown and may be related to autoimmunity, genetics, melanocyte self destruction, neuropsychiatric factors and keratin-forming cell dysfunction, etc. Therefore, a few vitiligo patients will be accompanied by hyperthyroidism, or hypothyroidism, lupus erythematosus, multiple myeloma, pernicious anemia and other diseases, which may be the cause or etiology of vitiligo and can be life-threatening, but vitiligo itself is not life-threatening.