If there is some kind of triggers appearing it may cause minor triple positive to become major triple positive. Minor triple positive refers to hepatitis B patients who are positive for the first, fourth and fifth items of the five items of hepatitis B, and the hepatitis B virus is not actively replicating in the body. Major triple positive is when the first, third and fifth items of hepatitis B are positive and the hepatitis B virus is actively replicating in the body. For patients with minor triple positive, minor triple positive may turn into major triple positive if certain triggers appear, such as irregular work and rest, alcohol abuse, low immunity due to pregnancy, or sudden occurrence of other diseases. If hepatitis B patients find that minor triple positive has become major triple positive, they need to consult a doctor in time, complete the quantitative viral DNA, liver function, liver ultrasound and other tests under the guidance of the doctor, and then the doctor will decide whether antiviral treatment is needed according to the results of the examination.