Patients with bronchiectasis can choose first- and second-generation cephalosporins, such as cefuroxime, cefazolin, cefadroxil, and so on. However, these are not absolute, and the most sensitive antibiotics should be selected for treatment according to the clinical characteristics of the patient and the results of sputum bacterial culture and drug sensitivity tests. For young and strong bronchitis patients, most of them are gram-positive bacterial infections, and it is better to choose first- and second-generation cephalosporins. However, for elderly patients with chronic bronchitis, many are combined with Gram-negative bacteria, the effect of these two types of cephalosporins is not particularly obvious, you can choose cefoperazone, ceftriaxone, cefotaxime and so on, and also need to choose the drug according to the results of bacterial culture and drug sensitivity test.