In clinical practice, it is often observed that the clinical symptoms and signs of some patients completely disappear, but the blood and urine amylase continue to be at a high level, and in some patients the duration of elevated blood amylase is even more than 1 month. In these patients, even if the transoral diet is resumed earlier, there is usually no recurrence of acute pancreatitis. Therefore, in patients with acute pancreatitis with persistent abnormal blood and urine amylase, the patient’s condition should be carefully analyzed and should not be denied food as a generalization, and complete normalization of blood and urine amylase activity is not clinically considered as a necessary condition for open diet.