Sinus premature beats commonly used drugs are metoprolol, trimetazidine and propafenone, etc. Patients should go to the hospital as soon as possible, and choose different drugs under the doctor’s advice for treatment. If the sinus premature beats are caused by coronary artery disease, heart valve disease, congenital heart disease and other diseases, patients should first target the primary disease for treatment, and at the same time choose lidocaine, amiodarone, metoprolol and other drugs to treat the symptoms of premature beats. If the patient has a lot of sinus premature beats, very serious, hemodynamics is very unstable, you can choose radiofrequency ablation surgery. Sinus premature beats are relatively rare and refer to abnormal heart beats that originate in the sinus node, earlier than those caused by normal cardiac electrophysiologic signals. If recurrent discomfort occurs, early medical attention is recommended to avoid delay.