Frequent atrial premature beats in duplex rhythm often have many reasons, mainly physiological factors, electrolyte disorders, adverse drug reactions, cardiac organic diseases and so on. 1. Physiological factors. Stress, emotional excitement, excessive anxiety, overwork, smoking, excessive alcohol consumption, drinking strong tea may cause frequent atrial premature beats. 2. Electrolyte disorders. Commonly, hypokalemia, hyponatremia, hyperkalemia, etc. may also occur. 3. Drugs. For example, excessive use of digitalis drugs such as digoxin may also cause frequent premature atrial contractions. 4. Organic heart disease. For example, ischemic cardiomyopathy, dilated cardiomyopathy, hypertrophic cardiomyopathy, angina pectoris, acute myocardial infarction attack, may be frequent atrial premature beats. In addition, atrial premature beats may occur in hyperthyroidism. Frequent atrial premature beats in dystonic rhythm should be treated promptly by a doctor.