If panic attacks and chest tightness are present, a test should be done, such as ECG exercise panel, cardiac ultrasound, all of which are done and still no problem is detected, it may be a manifestation of anxiety disorder, which is a panic attack. Of course it may also be combined with chest tightness, breathlessness or hand numbness, hand tremor, etc. If this condition exists, then it is considered functional, that is, cardiac neurosis. If the condition is relatively mild, such as once a month or once every two months, then of course there is no need to intervene, or use alprazolam temporarily during the attack. However, if the attacks are frequent, with daily panic attacks, chest tightness and breathlessness, anti-anxiety medication should be used. But the choice of specific drugs, the doctor according to the patient’s age, economic status, including the presence of underlying diseases, to determine the choice of drugs.