Xiao Chai Hu granules are effective in relieving heat from the exterior, draining the liver and harmonizing the stomach. It is a modern form of Xiao Chai Hu Tang, a classic formula in the Treatise on Typhoid Fever by Zhang Zhongjing, a famous medical scientist in the Han Dynasty of China. It is used clinically in Chinese medicine for the treatment of exogenous diseases and evidence of evil offending Shaoyang, manifesting as cold and heat exchanges, bitter fullness in the chest, loss of appetite, heart trouble and vomiting, bitterness in the mouth and dryness in the throat, and dizziness in the eyes, etc.,. Through clinical observation and treatment experience, Xiao Chai Hu granules can be used to treat the following diseases [1-2]: ① chronic gastritis; ② Meniere’s disease; ③ mouth bitterness; ④ periodic fever; ⑤ urinary tract infection; ⑥ allergic skin disease; ⑦ menopausal syndrome; ⑧ primary dysmenorrhea; ⑨ chronic nephritis, etc. Since the manifestation of “Shaoyang syndrome” in Chinese medicine can be reflected in many diseases in modern medicine, the clinical application of Xiao Chai Hu granules is also more extensive. For specific applications, please refer to the diagnosis and guidance of physicians in clinical practice.