Acute anterior interstitial wall myocardial infarction belongs to a kind of acute myocardial infarction, and it is recommended that patients take medication, surgical treatment, and general measures of conditioning for treatment. 1. Drug treatment: patients with acute myocardial infarction can follow the doctor’s instructions to use pethidine hydrochloride, morphine hydrochloride and other opioid receptor agonists for pain relief and sedation, but also can use metoprolol tartrate, bisoprolol fumarate tablets and other β-blockers to reduce the oxygen consumption of the myocardium, heparin, low molecular heparin, aspirin, clopidogrel and other anti-thrombotic drugs, statin lipid-lowering drugs and so on. 2. Surgery: patients with acute myocardial infarction can be treated with percutaneous coronary intervention, emergency coronary artery bypass grafting, thrombolysis, etc. when necessary. 3. General measures: patients with acute myocardial infarction should ensure adequate rest and avoid exercise, which can reduce the heart load. Patients with acute myocardial infarction should go to the emergency room of the hospital and be treated under the doctor’s guidance, avoiding blind medication. Patients should monitor their condition at any time and follow up on time.