Jaundice in preterm infants is first distinguished from physiological jaundice and pathological jaundice. Physiological jaundice in preterm infants is mild and begins to appear 3-5 days after birth, peaks in 5-7 days, and subsides in 7-9 days, with a remission time of no more than 4 weeks. If the jaundice is pathological, the treatment is more timely and effective, and the remission time usually does not exceed 4 weeks. The commonly used treatments are blue light irradiation to reduce jaundice, intravenous application of albumin to reduce free bilirubin, and hemolytic jaundice requiring propylene glycol to block hemolysis. Pathological jaundice in preterm infants must be intervened in a timely manner because the blood-brain barrier in preterm infants is poorly developed, the liver has poor metabolic capacity, and the chance of bilirubin encephalopathy is significantly higher than in full-term infants, so the treatment is more aggressive.