Acute symptoms of cerebral leukoedema usually subside within two weeks, but moderate to severe cerebral leukoedema may have sequelae.
Cerebral leukoedema usually manifests after the birth of a preterm infant, with an early presentation of strong echogenicity of cranial ultrasound, caused by edema. Acute symptoms of cerebral leukoedema usually subside within two weeks. This is immediately followed by anechoic cystic cavity formation and later by significant neurologic sequelae such as spastic cerebral palsy.
In general, severely ill preterm infants are at high risk of developing cerebral leukoedema. There is no specific treatment for leukoencephaloedema, which is mainly symptomatic. Therefore, the most important thing for premature infants with leukoencephaloedema is to follow up regularly for early detection of neurological developmental abnormalities and early rehabilitation.