Premature infants are those born at a gestational age of 28 weeks and less than 27 weeks, with a birth weight of less than 2500g. The smaller the gestational age and the lighter the birth weight, the worse the prognosis for preterm infants. Can preterm babies be mentally retarded? In addition to low intelligence, premature babies have immature immune systems and insufficient resistance, which can cause respiratory distress syndrome, asphyxia, infections, and nutritional deficiencies, all of which can cause brain hypoxia and lead to cerebral palsy and epilepsy in premature babies, resulting in abnormal intellectual development. It is important to note that the mental development of preterm infants must be assessed in terms of corrected age (corrected age = age at birth – (40 weeks – gestational weeks at birth)/4). In other words, if a little baby born prematurely at 32 weeks is 3 months old, his corrected gestational age should be 1 month, as long as his development is the same as that of a child born normally at full term for 1 month, it is normal. However, in order to reduce its prevalence, parents of preterm babies should still be guided by their health care providers and should go to the hospital for regular checkups. Generally speaking, by the age of 2 weeks should be consistent with the normal baby development, if still lower than normal age children, should pay high attention to whether there is really a problem of abnormal intellectual development. Therefore, parents should have confidence in their children and make timely all-round intervention for their children’s intelligence. As long as parents of premature babies seize the right time and methods, there is no difference between the intelligence of premature babies and full-term children.