The etiology of clubfoot has both congenital and acquired effects. The common feature is a foot deformity in which the arch of the foot is low or disappears, the affected foot is turned out and the arch collapses when standing and walking, and symptoms of fatigue or pain occur. Congenital factors are caused by abnormal development of bones, ligaments and tendons and fascia, including intra- navicular fusion and vertical talus, congenital foot ligament muscle laxity and exostosis. Acquired factors, including various causes of local anatomical position changes, long-term bedridden lack of exercise, calf and foot muscle atrophy can not maintain the arch tension, long-term weight-bearing standing, weight gain, long distance travel, excessive fatigue, resulting in related tissue fatigue gradually weakened, the arch gradually low, and then long-term weight-bearing standing, with foot bone disease, such as rheumatoid arthritis, bone and joint tuberculosis, etc. diseases, can also lead to local bone destruction. In addition, there is an imbalance of the medial and lateral muscles of the foot in poliomyelitis, leading to a state of flatfoot syndrome. There are also specific flatfoot syndromes that can be caused by post-polio and cerebral palsy sequelae. Flatfoot syndrome has acquired factors that lead to the state, so it is important to make timely adjustments during the treatment of related diseases to avoid the occurrence of flatfoot syndrome.