The decrease of local resistance of vagina causes the multiplication of anaerobic bacteria, which leads to Gardnerella infection. The decrease of local resistance of vagina is mainly related to the following factors: 1. long-term medication leads to decrease of local resistance and dysbiosis; 2. failure to strengthen local care of vulva in daily life, failure to pay attention to hygiene during sex or circumcision of sexual partner may cause decrease of local resistance and lead to anaerobic infection. Anaerobic bacteria infection, causing a large number of reproduction caused by the corresponding symptoms, such as will appear increased vaginal discharge, vaginal discharge has a great fishy odor, it is recommended to give the corresponding treatment, the symptoms will be relieved.