The onset of the disease is mostly in the age group of 50-59 years, with slightly more women than men. The onset of the disease is mostly acute, with only mild diarrhea in mild cases, but in severe cases, the disease can be violent and progress rapidly.
1. Diarrhea is the main symptom, mostly occurring within 4 to 10 days after the application of antibiotics, or within 1 to 2 weeks after the discontinuation of drugs, or 5 to 20 days after surgery. The degree and frequency of diarrhea varies. In mild cases, the stools are 2 to 3 times a day and may heal spontaneously after discontinuation of antibiotics. In severe cases, there is a lot of diarrhea, stools can be more than 30 times a day, sometimes diarrhea can last 4 to 5 weeks, a few cases can discharge plaque pseudomembrane, blood stool is rare.
2, abdominal pain is a more common symptom. Sometimes it is very severe and can be accompanied by abdominal distension, nausea and vomiting, so that it can be misdiagnosed as acute abdomen, surgical anastomotic leak, etc.
3. Toxemia manifestations include tachycardia, fever, delirium, and disorientation. In severe cases, hypotension, shock, severe dehydration, electrolyte imbalance, and metabolic acidosis, oliguria, and even acute renal insufficiency often occur.