High blood pressure with normal lipids may be secondary to hypertension and is also related to other factors such as long-term mental stress. Usually abnormal blood lipid may induce hypertension, but there are many reasons for high blood pressure, not only related to abnormal blood lipid. As for the patients with high blood pressure in the case of normal blood lipid, it may be secondary hypertension, which is usually seen in renal diseases such as glomerulonephritis, chronic pyelonephritis, and endocrine diseases such as menopausal syndrome, pheochromocytoma, or cranial and cerebral pathologies such as traumatic brain injury, brain tumor, and so on. At the same time, high blood pressure may also be due to sleep apnea syndrome, erythrocytosis and cardiovascular lesions such as aortic valve closure insufficiency and aortic constriction. And when the patient is in long-term anxiety, panic, tension, depression, irritability and other bad moods, it will make the body sympathetic nerve excitation, which will appear in the situation of high blood pressure. It is recommended that patients with normal blood lipids and high blood pressure should consult a doctor in time to find out the cause of the disease and take reasonable treatment measures according to the doctor’s instructions.