The manifestations of diabetic foot include decreased sensation and numbness in the affected limbs, infection, ulcers or destruction of tissues in the feet, etc. Symptoms of sepsis include fever, tachycardia, shortness of breath, etc. Prompt medical attention is recommended. The diabetic foot is usually caused by poor long-term glycemic control. The diabetic foot refers to the infection, ulcer formation and/or deep tissue damage in the lower extremities of diabetic patients due to the combination of neuropathy and varying degrees of vasculopathy. Diabetic foot with the development of the disease may induce sepsis followed by symptoms of sepsis, such as chills, high fever, tachycardia, shortness of breath, drop in blood pressure, decreased urine output, elevated white blood cells, and so on, and in severe cases, it may induce infectious shock, and even threaten the patient’s life. It is recommended to go to the hospital when the above symptoms occur and be treated under the guidance of the doctor.