Numerous studies have confirmed that most chronic liver diseases are accompanied by liver fibrosis, and some of these patients will go on to develop cirrhosis, but some patients do not know enough about liver fibrosis and cirrhosis, either once they hear that they have liver fibrosis or cirrhosis, they will talk about tiger, worry about it, and lose their minds; or they will be indifferent and let it go. First of all, we need to understand liver fibrosis or cirrhosis. Liver fibrosis is not the name of the disease, but a variety of chronic liver disease is often accompanied by a liver pathological changes. Common sense tells us that when flesh and skin are damaged, the body often uses scarring to repair it. In chronic liver disease, after liver damage caused by repeated inflammation, the body will repair in the same way. Scars are mainly composed of fibrous tissue, and the scarring process is the process of fibrosis. The more scars there are, the more fibrosis there is, and the liver gradually changes from soft to hard. If the liver is filled with a large amount of fibrous tissue, the typical pathological changes occur and it becomes cirrhosis. Therefore, liver fibrosis develops along with chronic hepatitis and is a kind of pre-cirrhotic lesion, which is related to cirrhosis from quantitative to qualitative changes. Therefore, cirrhosis is not formed suddenly, it is gradually aggravated by liver fibrosis. The formation of liver cirrhosis can cause two major hazards: First, due to the destruction of liver tissue structure, the intrahepatic blood vessels are distorted by compression, atresia or “short-circuit” anastomosis between arteries and veins, resulting in portal hypertension, leading to splenomegaly, ascites and esophagogastric fundic varices. There is a potential risk of bleeding from ruptured varices in the upper gastrointestinal tract; secondly, the blood microcirculation channels between normal liver cells are narrowed due to the deposition of fibrous tissue components and other factors, resulting in microcirculation disorders, which affect the blood supply to liver cells, making it difficult to repair damaged liver cells due to inflammation or even aggravate the damage, until the normal functioning liver cells become fewer and fewer, finally leading to liver failure. Both hazards are fatal. Cirrhosis is the end-stage of most chronic liver diseases, where the liver becomes hard in texture due to large deposits of fibrous tissue and the spleen is enlarged. The early stage of cirrhosis is a compensatory stage, when the liver still has enough capacity to sustain the needs of life. Patients may have no symptoms and signs, transaminase activity may be elevated, bilirubin may increase, serum albumin and pre-albumin may decrease, prothrombin time may be prolonged, and platelet count may decrease. If a patient with cirrhosis develops ascites, it means that the cirrhosis has entered the stage of decompensation and is “unable to sustain life”, barely coping with it and losing sight of it. The previous view was that liver fibrosis and cirrhosis were incurable diseases and that there were few options for treating liver fibrosis and compensated cirrhosis, except for treating the complications. In recent years, this view has changed. The view that liver fibrosis can be reversed and even cirrhosis can be reversed is gradually gaining recognition. Nowadays, liver fibrosis or cirrhosis is not a terminal disease, and patients do not need to lose confidence and should actively cooperate with their doctors in treatment. In order to avoid or reduce the harm of disease progression, patients with chronic liver disease are advised to receive anti-fibrotic treatment as early as possible.