Inflammation of the male reproductive tract can lead to obstruction of the sperm duct, mostly the epididymal duct, resulting in male infertility. Clinically, microsurgery can be performed to anastomose the obstructed proximal epididymal duct and distal vas deferens to reopen the seminal tract and ensure the smooth discharge of sperm. Vasectomy epididymal duct anastomosis is known as the most challenging microscopic anastomosis technique, and the operator must not only be technically proficient, but also be able to keep his fist in his hand and his mouth in his mouth. For those who recanalize after vasectomy, the surgery can be performed directly, and depending on the appearance of the proximal fluid of the obstruction and the microscopic performance during the surgery, either vasectomy or vasecto-epidididymal anastomosis can be chosen; for obstructive azoospermia caused by inflammation of the reproductive tract or medical factors, testicular biopsy must be performed before the reconstructive surgery to confirm good spermatogenic function, and scrotal exploration is performed first during the surgery, and if If no spermatozoa are found in the proximal vas deferens, vas deferens epididymal anastomosis is then chosen; for patients with congenital absence of the vas deferens, epididymal sperm extraction is usually used for assisted reproduction. Currently, the classic vas deferens epididymal anastomosis is the two-stitch method with end-lateral overlay, and Cornell recently reported that its recanalization rate can reach over 90%. First, four microdots are marked on the vas deferens surface; two parallel double-stitched sutures are inserted through the dilated epididymal duct at one end, the epididymal duct is incised longitudinally before exiting, the presence of spermatozoa is confirmed and microscopic spermatozoa are aspirated and frozen, and the two sutures are passed through the lumen of the vas deferens to the pre-marked microdots; the sutures are drawn tightly and the epididymal duct is overlaid into the lumen of the vas deferens. The suturing procedure follows the universal principles: mucosa to mucosa; no tension; ensuring blood supply; and no injury.