The causes of irregular vaginal bleeding during non-menstrual periods are physiological and pathological. The following are the physiological irregular bleeding and pathological irregular bleeding during non-menstrual period respectively. I. Physiological irregular bleeding during non-menstrual period: Ovulation bleeding: women’s ovulation period is the middle of two menstrual periods, i.e. about 15 days before the onset of menstruation. Due to the fluctuation of hormone level during ovulation, ovulatory bleeding may occur. At this stage, the bleeding may be a small amount of spotting bleeding, which will last for 2-3 days and will be clean, accompanied by lower abdominal cramping, which is normal and can be temporarily observed. Pathological non-menstrual irregular bleeding: 1. abnormal pregnancy-related bleeding: abnormal vaginal bleeding in women of childbearing age should be ruled out first, such as pre-eclampsia, ectopic pregnancy, placenta praevia, chorionic carcinoma, postpartum placenta residue, etc., which can be ruled out by urine pregnancy test and ultrasound examination; 2. inflammatory bleeding: such as vaginitis, cervicitis, etc., perform routine leucorrhoea test to clarify the type of disease, and actively apply antibiotic drugs for anti-inflammatory treatment. If there are endometrial polyps, hysteroscopic surgery can be performed; 3, tumor bleeding: such as submucosal fibroids, cervical cancer, endometrial cancer, fallopian tube cancer, etc. are characterized by irregular bleeding. In case of submucosal fibroids, myomectomy can be performed, and in case of endometrial cancer or cervical cancer, surgery or radiotherapy will be given after evaluation. 4. Bleeding from endocrine disorders: such as anovulatory uterine bleeding or luteal insufficiency or luteal atrophy, etc., treatment can be progesterone capsules or estrogen capsules. When the above symptoms occur, especially postmenopausal women with vaginal bleeding, they should go to the hospital for examination in time to identify the cause and treat the cause.