Nocturia caused by prostate hyperplasia can lead to patients urinating up to three times or more a night, which may cause insomnia. Prostatic hyperplasia is one of the common diseases in middle-aged and old-aged men. The cause of the disease has not been clearly defined, and it is mainly related to the role of sex hormones and their receptors, the imbalance between cell proliferation and apoptosis, and the role of growth factor neurotransmitters, etc. The patient’s typical symptoms are frequent urination and increased nocturia. Typical symptoms of patients are frequent urination, urinary urgency and increased nocturia. Nocturia caused by prostate hyperplasia is manifested as an increase in the number of urination at night, but the amount of urine is not much each time, and patients may have to urinate more than 3 times a night, which will affect the quality of sleep and cause insomnia, thus resulting in the next day’s fatigue and lack of energy. For patients with prostate hyperplasia, when the symptoms of excessive nocturia appear, they should actively cooperate with doctors to carry out standardized treatment to avoid interfering with sleep, otherwise it will affect normal life.