1. Patients with optic neuritis should be aware of the risk of multiple sclerosis. For patients with optic neuritis, MRI is an important auxiliary examination, which can help determine whether there is a combination of MS and exclude other lesions. Risk factors for MS in optic neuritis: (1) single or multiple white matter lesions on MRI; (2) atypical neurologic signs; (3) recurrent episodes or a family history of MS. 3. Even in the presence of brain lesions, only 50% of patients have clinical manifestations of MS. Like most diseases, optic neuritis also has a “favored” group of people: (1) women: women are the most common group of optic neuritis, especially women aged 18-49 years. There are about three times as many female optic neuritis patients as male optic neuritis patients. (2) Patients diagnosed with multiple sclerosis (MS): People diagnosed with MS are at high risk for optic neuritis. Optic neuritis is often the first manifestation of MS. Optic neuritis can occur either as the first symptom of multiple sclerosis (MS) (1/4) or alone, or secondary to the course of the disease. Among patients with optic neuritis, 8.7% develop MS during the course of the disease, and this rate increases yearly (30% at 5 years of follow-up and up to 58% at 15 years of follow-up). Of these, only a few cases resolved spontaneously. Long-term follow-up shows that 2/3 of women and 1/3 of men with optic neuritis eventually develop MS, and statistics show that the risk of MS after an attack of optic neuritis is as high as 13% to 58%. There is no authoritative data to prove that women with a sweet tooth are more likely to develop optic neuritis. The rumor may be related to the fact that the metabolism of sugar in the body requires vitamin B1, as vitamin B1 deficiency may be an important cause of optic neuritis. However, it is certain that a sweet tooth is detrimental to health.