A patient with esophageal cervical spondylosis was admitted to the Department of Anesthesia and Pain. The woman was only 38 years old, but she had been suffering from chronic “pharyngitis” symptoms for 10 years, mainly manifesting as throat and esophageal symptoms such as dryness, pain in the throat, obvious foreign body sensation, difficulty swallowing, and hoarseness. By chance, he was told by a friend that his voice was better than before after the treatment of cervical spondylosis at the Second Hospital, so he went to the pain clinic of Director You with the psychology of trying. After a detailed consultation and X-ray, Director You initially diagnosed cervical spondylosis of the esophagus type. Later, the CT results (cervical 4 and 5 disc protrusion) further confirmed the diagnosis, and the cause was really found. These symptoms were significantly reduced after paravertebral nerve block. Subsequently, intralesional instillation therapy and CT-guided minimally invasive intervention for cervical disc collagenase lysis were performed. When the patient was discharged seven days later, her symptoms of pharyngitis, which had been bothering her for many years, had completely disappeared, and she was very grateful and highly praised our pain treatment technology. Esophageal cervical spondylosis is less common than other types of cervical spondylosis and often fails to attract attention because of the patient’s limited general knowledge. The symptoms of the disease are not typical, and the common symptoms are similar to “pharyngitis”, which can easily lead to misdiagnosis of the disease. Warm tip: go to a regular hospital to receive regular treatment, so as not to delay a minor disease into a major one and miss the time for treatment.