How to eliminate the patient’s fear of this diagnostic measure in time is the key to the successful implementation of this technique. First of all, patients should be made to understand the great significance of this test for the diagnosis, treatment and prognosis judgment of the disease. Because renal pathology is the gold standard for the diagnosis of renal diseases, clinical diagnosis and pathological types are both correlated but also disparate, and the treatment plans for various different pathological types are very different, so only after obtaining correct diagnostic information can a targeted treatment plan be developed to finally obtain clinical cure and maximum remission; secondly, it should be explained to patients that this diagnostic technique has been applied for many years at home and abroad and clinically Secondly, it should be explained to the patient that this diagnostic technique has been used for many years at home and abroad and has been clinically proven to be safe, so as to obtain the cooperation of the patient and his family as soon as possible. In addition, after the patient has obtained understanding and consent for renal biopsy, attention should be paid to various preoperative preparations, such as training to hold the breath after a deep exhalation, which is generally required to be around 20 seconds in order to provide a more relaxed operating time for the operator. It should be repeatedly emphasized that during the breath-holding period, no slow deflation should be allowed to prevent changes in the position of the kidney that has moved downward after deep inspiration, no random body movement, coughing and speaking, and if there is discomfort that requires activity and breathing, hand signals and bed patting should be done first to enable the operator to stop the operation in time to avoid damage to the kidney. Finally, it should be emphasized that all western anticoagulation and Chinese medicine to activate blood stasis drugs should be stopped for 1 week, platelets and coagulation mechanism are normal before kidney biopsy! Song Chun-dong, Department of Nephrology, The First Affiliated Hospital of Henan College of Traditional Chinese Medicine